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Corneal Collagen Crosslinking For Keratoconus

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Other Conditions That Can Benefit From Scleral Contact Lenses:

  • Corneal Ecstasia
  • Severe Dry Eyes
  • Sjorgen’s Syndrome
  • Stevens – Johnson syndrome
  • Pellucid Marginal Degeneration
  • Post Lasik Complications
  • Graft versus host disease
  • Post RK Complications
  • Severe Eye Allergies
  • Neurotrophic keratopathy
  • Post PRK Complications

Is Corneal Collagen Cross-Linking A Recommended Treatment For Keratoconus?

For most patients with corneal irregularities such as Keratoconus, Corneal Cross-Linking may be unnecessary and ineffective. Researchers have raised questions about the efficacy of Corneal Collagen Cross-Linking, such as this research paper that analyzed 219 eyes with Keratoconus.

The author of the study concluded:

“The evidence for the use of CXL in the management of keratoconus is limited due to the lack of properly conducted trials”.

The most effective option for patients with Keratoconus or other Corneal Irregularities is custom made large diameter scleral lens specialty contact lenses which substantially improve visual clarity and comfort.

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Helping Patients With Keratoconus & Corneal Irregularities

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What is Corneal Collagen Crosslinking?

CXL is a surgical process to strengthen the cornea for patients with keratoconus, PMD, and post-LASIK ectasia. The procedure is minimally invasive, whereby the eye doctor combines liquid B12 with UV light to reduce the ectasia, the bulging and thinning of the cornea.


What is the process of Corneal Collagen CrossLinking?

The procedure, performed by a surgeon, is a quick 30-minute procedure. The surgeon will apply local anesthetic, liquid vitamin b12, and 10 minutes of controlled UV exposure. The procedure is considered extremely minor, with minor symptoms that usually clear up quickly.


What Are Scleral Lenses

While many tout CXL as the next big thing for corneal irregularity, many eye doctors say that Scleral lenses are a far more effective solution for most patient with Keratoconus or other conditions. Scleral Contacts are mapped to your eye and vault over the sensitive cornea to rest on the white Sclera of the eye, in the process creating a pocket for lubricating liquid.

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Q&A On Corneal Collagen Cross-Linking (CLX)

Is Corneal Cross Linking Dangerous?

Independent research noted that  “adverse effects were not uncommon but mostly transient and of low clinical significance”.

According to the safety studies done by the pharmaceutical companies:

“In progressive keratoconus patients, the most common ocular adverse reactions in any CXL-treated eye were corneal opacity (haze), punctate keratitis, corneal striae, corneal epithelium defect, eye pain, reduced visual acuity, and blurred vision.

In corneal ectasia patients, the most common ocular adverse reactions were corneal opacity (haze), corneal epithelium defect, corneal striae, dry eye, eye pain, punctate keratitis, photophobia, reduced visual acuity, and blurred vision. These events are expected sequelae following epithelial corneal debridement and occurred at a higher incidence than observed in control patients, who did not undergo debridement or exposure to UVA light”


Is Corneal Collagen Cross Linking covered by insurance?

While still a very new procedure, there are currently 30 insurances covering 90 million Americans that cover the expense of Corneal Collagen Cross-Linking. 

Are There Different Types of Corneal Collagen Cross Linking?

There is currently only one company, Avedro, with FDA approval for use with patients that have Keratoconus. Many surgeons will use other products, without FDA approval, as an “off-label” option.

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